Endocrine Abstracts

Scleredema diabeticorum is an infrequently seen connective tissue disorder that effects upper part of the body. The affected skin is thick, hard and painless. A 51-year-old male Type 2 diabetic patient was referred to our department for infected foot ulcer. On physical examination erythematous, hard, painless, wide-reaching skin lesion on his upper back and shoulders except from draining diabetic foot ulcer on his right foot first and second fingers. Multipl subcutanously insu...

Introduction: The COVID-19 pandemic resulted in various outcomes that have altered disease prevalence and drug utilization patterns. Our study aimed to evaluate the trends in the utilization and costs of antidiabetic medications before and during the COVID-19 outbreak in Turkey.Methods: We obtained nationwide sales data for antidiabetics from IQVIA Turkey, spanning between April 2018 and March 2022. Mean monthly drug utilization and expenditure trends be...

Aim: Vitamin D deficiency is reported as a risk factor for the development of diabetes in several epidemiologic studies. In this study, we investigated the frequency of 25-OH vitamin D deficiency in type 2 diabetes and the relationship between 25-OH vitamin D deficiency and microvascular complications.Materials and methods: Retrospectively, medical records of 557 type 2 diabetic patients admitted to the Endocrinology Outpatient Clinic in January–Mar...

Aim: In this study our aim was to investigate the relationship between obesity and vitamin D and hyperparathyroidism.Material and Method: 127 healthy persons included in this study. Study group were divided into four groups according to body mass index (BMI). Group 1 (n=35) BMI 18.5–24.9 kg/m2, Group 2 (n=35) BMI 25–29.9 kg/m2, Group 3 (n=35) BMI 3.0–34.9 kg/m2, Group 4 (n=22) BM...

Aim: The relationship between hyperprolactinoma and insulin resistance has been shown in many studies. It is also known that hyperprolactinoma causes changes in carbohydrate and lipid metabolism. The aim of our study is to evaluate insulin resistance in patients with prolactinoma and see the effect of treatment on insulin resistance and karotis intima media thickness (CIMT).Material and methods: Twenty-two female patients diagnosed biochemically and radi...

Aim: Radioactive treatment after surgery forms the basis of treatment of differentiated thyroid cancers (DTC) and also used as permanent theraphy of hyperthyroidism. Iodide is being transported into the thyrocytes by the NIS system that located on the thyrocytes’ cell membran. NIS system also has been shown at the gastric mucosa. In this study we proposed to analyse the effect of low and high dose radio-iodine treatment on Helicobacter pylori eradication.<p cla...

Aim: Neopterin is a mareker of inflammation secreted from monocytes and macrophages. It is found to be increased in malignant diseases. The aim this study was to evaluate the urine neopterin levels in thyroid cancer.Materials and methods: Sixty nine patients with thyroid cancer, 76 patients with benign thyroid pathology and 33 healthy subjects were evaluated. First morning urine samples were collected from the patients and the normal subjects for neopter...

Nontraumatic rhabdomyolysis is mostly caused by drugs, alcohol consumption or compression of muscles. Severe hyperosmolarity rarely can cause rhabdomyolysis. Our case has santral diabetes insipidus that has admitted with the clinical picture of rhabdomyolysis.Case: Twenty-six-years old male has admitted to our clinic with the complaint of weakness, nausea, vomitting, polydipsia, polyuria, difficulty in walking and tendency to sleep. Neurologic examinatio...

Although Diabetic ketoalkalosis (DKAlk) has beendescribed as a mixed acid-base disorder over half a century ago, there is unawareness among physicians. Here, we present two cases to emphasize DKAlk which is more common than it’s thought.Case-1: A thirty-year-old female patient with type-1 diabetes and ten weeks of pregnancy presented with several weeks of vomiting. She also reported that she had hyperthyroidism for 2 weeks and that she used propylt...